流感快速参考（第2版）：Rapid Reference to Influenza 下载 fb2 pdf rb kindle 115盘 极速 azw3

　　The ongoing threat of pandemic influenza is very serious indeed as evidenced by recent articles within The Lancet and The Lancet Infectious Disease. This title provides the reader with authoritative and accessible information on the subject of influenza. Clearly written by key experts in the field and highly illustrated in full colour, the book provides an overview of influenza, its pathogenesis, epidemiology, the burden of disease and its health economics. Rapid Reference Influenza also summarises available information on the molecular biology of influenza and the emergence of new influenza viruses. Completely updated with the latest information on H5N1, the book aims to contribute to international efforts to emphasize the major burden of influenza and the need for better control.

Expert information succinctly written for ease of use.

Abundant use of bulleted lists and short tables, for quick access to comparative information.

Presents evidence-based sources for practice when available, either through research or best-practice guidelines.

Completely up-to-date in light of the H5N1 emergence and spread.

Useful addresses and websites appendix provide additional resources for the physician.

Updated epidemiology regarding H5N1.

Revised discussion about the relevance of the potential impact of H5N1.

Latest statistics from the World Health Organization.

Upda te on 'pandemic preparedness' and related issues including new vaccine development.

Includes an overview of current 'global thinking' about the possible pandemic including reports from the recent meeting 　　between the WHO and the World Bank.

Biographies

Foreword

Foreword to the first edition

Acknowledgements

Abbreviations

1.Introduction

　The influenza virus

　Pandemics and epidemics

　Clinical picture and impact of flu

　Prevention and control

　References

2.The Influenza Virus: Structure and Replication

　Classification and nomenclature of influenza viruses

　Influenza virus structure

　Virus replication

　References

3.Influenza Epidemics and Pandemics

　Annual influenza epidemics

　Origin of influenza pandemics

　Influenza pandemics of the past

　Will there be a new pandemic?

　Influenza pandemic preparedness

　Concluding remarks

　References

4.The Immune Response to Influenza Infection

　The innate immune response

　Initiation of the adaptive immune response

　Effector mechanisms of the adaptive response

　Effect of ageing on the immune system

　References

5.Pathogenesis, Clinical Features and Diagnosis

　Pathogenesis of influenza

　Presentation of uncomplicated influenza

　Complications of influenza

　Influenza in susceptible subgroups

　Diagnosis of influenza

　References

6.Social and Economic Impact of Influenza

　Social impact

　Economic impact

　Impact of pandemic influenza

　References

7.Antivirals: Treatment, Prophylaxis and Pandemic Control

　Mechanisms of action of antivirals

　Antivirals in treatment and prophylaxis of influenza

　Development of drug resistance

　The role of antivirais in pandemic control

　References

8.Vaccination: Cornerstone of Influenza Control

　Current inactivated influenza vaccines

　Vaccination coverage

　Benefits of influenza vaccination

　How may influenza control be further improved?

　References

9.Vaccination: Novel Developments and Pandemic Vaccines

　Novel inactivated influenza vaccines with

　improved efficacy

　Mucosal delivery of influenza vaccines

　Novel approaches to vaccine virus production

　Pandemic vaccines

　References

Appendix 1-Useful Websites

Appendix 2-WHO Global Agenda for Influenza Surveillance and Control

Appendix 3-Position Paper on Influenza Vaccines

Appendix 4-Avian Influenza: Assessing the Pandemic Threat

Index

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作者简介：

　　Jan C Wilschut,PhD is Professor of Molecular Virology in the Department of Medical Microbiology at the University Medical Centre, Groningen, The Netherlands. His main research interests include the cell entry mechanisms of enveloped viruses, influenza virus and alpha- and flaviviruses in particular, and viral and tumour vaccine development. Based on his interest in viral membrane fusion processes, he developed the virosome system as a basis for novel vaccine modalities. He is Co-ordinator of the Netherlands Influenza Vaccine Research Centre (NIVAREC) and has published over 150 papers in international peer-reviewed journals.

书籍介绍

This book provides the reader with authoritative and accessible information on the subject of influenza. Clearly written by key experts in the field and highly illustrated in full colour, the book provides an overview of influenza, its pathogenesis, epidemiology, the burden of disease and its health economics. "Rapid Reference to Influenza" also summarises available information on the molecular biology of influenza and the emergence of new influenza viruses. Completely updated with the latest information on H5N1, the book aims to contribute to international efforts to emphasize the major burden of influenza and the need for better control.